Science History Publications/USA

From the Book: Figure 2

From the Book: Figure 8

Hormones of Life

Endocrinology, the Pharmaceutical Industry, and the Dream of a Remedy for Sterility, 1930–1970

Christer Nordlund

“…considers the realm of reproductive endocrinology development and hormone therapies and reveals the process of research and development as a whole. Any serious medical library needs this history, reminding of how the modern pharmaceutical industry developed.”—California Bookwatch, October 2011

CONTENTS

Foreword

Introduction

Premises and Questions

The New Physiology Before the Arrival of the New Biology

A Controversial Issue

Artifact Biography and Network Analysis

Consultation, Procuration, Standardization and Mediation

Sources and Scope

Outline

Tradition

Hormones and Hormone Therapy: Historical Background

Internal Secretion and Organotherapy

From Organotherapy to Endocrinology

Sex Hormones in Focus

New Methods of Production and Quality Control

Gonadotropin or Gonadotropins?

Axel Westman, Endocrinology, and the Population Question

Endocrinology and "Modern" Gynecology

Infertility as Endocrinological Problem

Population Policy and Sterility

Endocrinology as Public Science

Lion of the North: Leo and the First Hormone Drugs

The Birth of a Business

Leo's First Urine Collection Campaign

Leo's Wandering Hormone Lab

Innovation

Inventing Gonadex

The Second World War: A Turning Point for the Swedish Pharmaceutical Industry

Investing in a "Line of Hormones"

The Dream of a Pure Gonadotropin

The Development of "New Physex"

Registering Gonadex

Leos' Second Urine Collection Campaign

Launching Gonadex

Leo's Advertising Campaign

Selling Gonadex

A Conference for the Press

The Image of Hormonal Medicine as a Remedy for Sterility in the Press, Part I

The Reception of Gonadex

Reaction of the Medical Profession

Dr. Waldemar Gårdlund's Complaint

Hormones and Dreams

Gonadex and its Prospective Users

Verdict of the National Pharmaceutical Laboratory

"We Have Made Fools of Ourselves, Not Only in Front of Swedish Pharmacists and Physicians But the Whole World"

Development

New Gonadex

Shake-Up at the Women's Clinic

Hormone Therapy for Better or Worse

At the Crossroads

Making "New Gonadex"

The Royal Caroline Hospital Takes Over the Hormone Laboratory

More Than Gonadex

Axel Westman's Bovine Pituitary Implant

Carl Axel Gemzell's Human Pituitary Extract

Gonadotropin from Urine—One More Time

In the Shadow of Homogonal

Post-Menopausal Gonadotropin Put to the Test

Leo's Third Urine Collection Campaign

The Image of Hormonal Medicine as a Remedy for Sterility in the Press, Part II

"A Contract to Deliver hMG to the U.S.A. Has Been Signed"

Much Ado About Almost Nothing

Homogonal Launched in Sweden

Conclusion

Many Levels of Collaboration

The Identities of Gonadex

The New Physiology and the New Biology

Notes

Sources and Literature

name index

May 2011, 307 pp., illustrated, paperback, 978-0-88135-475-1, $34.95